node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Achl_0133 | Achl_2487 | Achl_0133 | Achl_2487 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | 0.992 |
Achl_0133 | Achl_2488 | Achl_0133 | Achl_2488 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.529 |
Achl_0133 | Achl_2493 | Achl_0133 | Achl_2493 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.424 |
Achl_0133 | Achl_2812 | Achl_0133 | Achl_2812 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: art:Arth_3111 uroporphyrinogen-III C-methyltransferase. | 0.717 |
Achl_0133 | gltX | Achl_0133 | Achl_2263 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.417 |
Achl_0133 | gluQ | Achl_0133 | Achl_3764 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate--tRNA ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.411 |
Achl_0133 | hemA | Achl_0133 | Achl_2495 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.988 |
Achl_0133 | hemC | Achl_0133 | Achl_2489 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.915 |
Achl_0133 | hemE | Achl_0133 | Achl_2494 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.654 |
Achl_0133 | hemL | Achl_0133 | Achl_2485 | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: art:Arth_2763 glutamate-1-semialdehyde 2,1-aminomutase. | 0.924 |
Achl_2487 | Achl_0133 | Achl_2487 | Achl_0133 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.992 |
Achl_2487 | Achl_2488 | Achl_2487 | Achl_2488 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.965 |
Achl_2487 | Achl_2493 | Achl_2487 | Achl_2493 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.736 |
Achl_2487 | Achl_2812 | Achl_2487 | Achl_2812 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: art:Arth_3111 uroporphyrinogen-III C-methyltransferase. | 0.936 |
Achl_2487 | gltX | Achl_2487 | Achl_2263 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.504 |
Achl_2487 | gluQ | Achl_2487 | Achl_3764 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | Glutamate--tRNA ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.420 |
Achl_2487 | hemA | Achl_2487 | Achl_2495 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.966 |
Achl_2487 | hemC | Achl_2487 | Achl_2489 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
Achl_2487 | hemE | Achl_2487 | Achl_2494 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.882 |
Achl_2487 | hemL | Achl_2487 | Achl_2485 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: art:Arth_2765 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: art:Arth_2763 glutamate-1-semialdehyde 2,1-aminomutase. | 0.996 |