STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OsJ_05367Eukaryotic initiation factor 4A-3; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity) (414 aa)    
Predicted Functional Partners:
OsJ_24703
Eukaryotic translation initiation factor 4G; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome
   
 0.997
OS04T0499300-01
Eukaryotic translation initiation factor isoform 4G-1; Plays a role in the accumulation of a sobemovirus (RYMV) during viral infection
   
 0.995
OS10T0569200-01
Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome
   
 0.982
OS06T0520600-01
Zinc finger CCCH domain-containing protein 43
   
 0.975
OsJ_07496
Eukaryotic translation initiation factor isoform 4G-2; Plays a role in the accumulation of a sobemovirus (RYMV) during viral infection
   
 0.968
OS02T0221300-01
Putative eukaryotic initiation factor 4a-2; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity)
  
  
0.963
OsJ_00175
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation
   
 0.957
OS01T0970400-01
Eukaryotic translation initiation factor 4E-1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Recognizes and binds the 7-methylguanosine- containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures
   
 0.956
OS10T0388900-01
Expressed protein; Os10g0388900 protein; cDNA clone:J033057B06, full insert sequence
   
 0.953
OS06T0571400-01
Elongation factor 1-gamma 3; Probably plays a role in anchoring the complex to other cellular components
   
 
 0.952
Your Current Organism:
Oryza sativa
NCBI taxonomy Id: 4530
Other names: O. sativa, Oryza sativa L., red rice, rice
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