STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme (By similarity) (440 aa)    
Predicted Functional Partners:
KU70
ATP-dependent DNA helicase 2 subunit KU70; Single-stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU70, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA (By similarity). Required for the maintenance of chromosome stability and normal developmental growth. Plays a role in maintaining telomere length. Acts as a negative regulator in telomere homeostasis
   
 
 0.983
OS08T0305300-01
Os08g0305300 protein; cDNA clone:J023087H17, full insert sequence
   
 
 0.969
KU80
ATP-dependent DNA helicase 2 subunit KU80; Single-stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU70, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA. Plays a role in maintaining telomere length. Acts as a negative regulator of telomerase (By similarity); Belongs to the ku80 family
   
 
 0.939
OS12T0613300-02
Myb-like DNA binding domain containing protein; Myb-like DNA-binding domain containing protein, expressed; Os12g0613300 protein; cDNA clone:J023108E10, full insert sequence
      
 0.936
OsJ_10972
OB-fold nucleic acid binding domain containing protein, expressed; Os03g0366900 protein; cDNA clone:J023098J07, full insert sequence
    
 
 0.918
OsJ_36635
G-patch domain containing protein, expressed; Os03g0253500 protein
   
  
 0.868
OS03T0370500-02
H/ACA ribonucleoprotein complex subunit 4, putative, expressed; Os03g0370500 protein; Putative centromere/microtubule binding protein; cDNA clone:001-113-E01, full insert sequence
    
 
 0.860
OS04T0576300-01
Os04g0576300 protein
    
 
 0.860
OsJ_25275
Os07g0636000 protein; Putative centromere/microtubule binding protein; cDNA clone:J033094C11, full insert sequence
    
 
 0.860
OS11T0598700-00
annotation not available
    
 
 0.860
Your Current Organism:
Oryza sativa
NCBI taxonomy Id: 4530
Other names: O. sativa, Oryza sativa, Oryza sativa L., red rice, rice
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