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Mvol_0035 protein (Methanococcus voltae) - STRING interaction network
"Mvol_0035" - SMC domain-containing protein in Methanococcus voltae
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Mvol_0035SMC domain-containing protein (1113 aa)    
Predicted Functional Partners:
mre11
Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3’-5’ exonuclease activity and single- stranded endonuclease activity (391 aa)
 
  0.999
Mvol_0037
Metallophosphoesterase (391 aa)
 
  0.999
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a ’key in a lock’ to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] (405 aa)
   
 
  0.991
Mvol_1508
Hypothetical protein (369 aa)
   
  0.987
Mvol_1013
tRNA/helicase-type nucleic acid-binding protein (643 aa)
   
  0.985
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] (327 aa)
 
  0.984
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (322 aa)
   
  0.979
radB
AAA ATPase; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (280 aa)
   
  0.962
hel308
DEAD/DEAH box helicase domain-containing protein; DNA-dependent ATPase and 3’-5’ DNA helicase that may be involved in repair of stalled replication forks (878 aa)
     
 
  0.960
top6A
DNA topoisomerase; Relaxes both positive and negative superturns and exhibits a strong decatenase activity (365 aa)
     
  0.950
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
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