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guaAB protein (Methanococcus voltae) - STRING interaction network
"guaAB" - GMP synthase [glutamine-hydrolyzing] subunit B in Methanococcus voltae
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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guaABGMP synthase [glutamine-hydrolyzing] subunit B; Catalyzes the synthesis of GMP from XMP (310 aa)    
Predicted Functional Partners:
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (498 aa)
 
  0.998
guaAA
GMP synthase [glutamine-hydrolyzing] subunit A; Catalyzes the synthesis of GMP from XMP (188 aa)
   
  0.994
hpt
Hypoxanthine/guanine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis; Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily (187 aa)
   
  0.955
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (176 aa)
   
  0.955
Mvol_0577
KEGG- cff-CFF8240_0351 anthranilate synthase component II; TIGRFAM- glutamine amidotransferase of anthranilate synthase; PFAM- glutamine amidotransferase class-I (193 aa)
   
  0.946
Mvol_1457
KEGG- hypothetical protein; TIGRFAM- non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM- Ham1 family protein; Belongs to the HAM1 NTPase family (196 aa)
   
 
  0.936
Mvol_1641
PFAM- PfkB domain protein; KEGG- hha-Hhal_1195 ribokinase-like domain-containing protein; Belongs to the carbohydrate kinase PfkB family (316 aa)
   
 
  0.929
surE
5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family (269 aa)
   
 
    0.910
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates (537 aa)
   
 
  0.856
purL
Phosphoribosylformylglycinamidine synthase subunit PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (740 aa)
   
   
  0.824
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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