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mptE protein (Methanococcus voltae) - STRING interaction network
"mptE" - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase in Methanococcus voltae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
mptE6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family (249 aa)    
Predicted Functional Partners:
mptD
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family (123 aa)
 
   
  0.973
Mvol_0911
KEGG- kpe-KPK_0638 metallo-beta-lactamase family protein (287 aa)
       
    0.903
Mvol_1194
PFAM- CoA-binding domain protein; KEGG- dat-HRM2_16770 SucD3 (707 aa)
 
          0.660
Mvol_1222
TIGRFAM- metal dependent phophohydrolase; PFAM- metal-dependent phosphohydrolase HD sub domain; KEGG- ank-AnaeK_2543 metal dependent phosphohydrolase; SMART- metal-dependent phosphohydrolase HD region (287 aa)
           
  0.632
Mvol_0003
UPF0218 protein Mvol_0003; PFAM- Protein of unknown function DUF359; Belongs to the UPF0218 family (172 aa)
   
          0.593
Mvol_1680
SMART- Nucleotide binding protein PINc; KEGG- predicted protein; K11883 RNA-binding protein NOB1 (208 aa)
   
          0.590
tiaS
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA (508 aa)
   
          0.584
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate (529 aa)
   
     
  0.581
Mvol_0044
KEGG- gsu-GSU1757 ribosomal-protein-alanine acetyltransferase; TIGRFAM- ribosomal-protein-alanine acetyltransferase; PFAM- GCN5-related N-acetyltransferase (161 aa)
              0.570
spt5
Transcription elongation factor Spt5; Stimulates transcription elongation (147 aa)
   
          0.565
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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