• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
tiaS protein (Methanococcus voltae) - STRING interaction network
"tiaS" - tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tiaStRNA(Ile2) 2-agmatinylcytidine synthetase TiaS; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA (508 aa)    
Predicted Functional Partners:
Mvol_0629
Putative HTH-type transcriptional regulatory protein Mvol_0629; KEGG- conserved hypothetical protein; PFAM- helix-turn-helix domain protein; SMART- helix-turn-helix domain protein (340 aa)
 
          0.850
polB
DNA polymerase II small subunit; Possesses two activities- a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3’ to 5’ direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family (619 aa)
   
     
  0.833
Mvol_1284
PFAM- phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG- mes-Meso_0990 exonuclease RecJ (468 aa)
   
     
  0.828
priS
DNA primase small subunit PriS; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthe [...] (369 aa)
   
     
  0.743
dnaG
DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication (603 aa)
   
     
  0.717
Mvol_0034
KEGG- retinitis pigmentosa GTPase regulator-like protein; PFAM- TOPRIM domain protein; SMART- Toprim sub domain protein (603 aa)
   
     
  0.717
Mvol_1444
PFAM- Protein of unknown function DUF655 (197 aa)
   
     
  0.679
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (269 aa)
         
  0.643
Mvol_0174
KEGG- hypothetical protein; TIGRFAM- RNA methylase, NOL1/NOP2/sun family; PFAM- Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family (322 aa)
         
  0.639
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate; Belongs to the TrpA family (270 aa)
           
  0.637
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
Server load: low (17%) [HD]