STRINGSTRING
Mvol_0356 protein (Methanococcus voltae) - STRING interaction network
"Mvol_0356" - Exodeoxyribonuclease III Xth in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mvol_0356Exodeoxyribonuclease III Xth (249 aa)    
Predicted Functional Partners:
Mvol_0867
DNA-(apurinic or apyrimidinic site) lyase (366 aa)
 
  0.997
pcn
Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (269 aa)
   
  0.989
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...] (327 aa)
     
  0.941
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (597 aa)
   
 
  0.939
Mvol_1508
Hypothetical protein (369 aa)
     
  0.905
Mvol_1013
tRNA/helicase-type nucleic acid-binding protein (643 aa)
     
  0.905
rfcS
Replication factor C; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA (314 aa)
   
  0.902
rfcL
AAA ATPase central domain-containing protein; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA (510 aa)
   
  0.902
polB
DNA-directed DNA polymerase; Possesses two activities- a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3’ to 5’ direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (619 aa)
     
 
  0.887
Mvol_0936
ERCC4 domain-containing protein (822 aa)
     
 
  0.871
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
Server load: low (6%) [HD]