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Mvol_0400 protein (Methanococcus voltae) - STRING interaction network
"Mvol_0400" - PFAM: Beta propeller domain in Methanococcus voltae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Mvol_0400PFAM- Beta propeller domain; Proteinase inhibitor I42, chagasin; KEGG- ade-Adeh_1856 hypothetical protein (798 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] (828 aa)
   
 
  0.874
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (269 aa)
   
 
  0.764
top6A
Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family (365 aa)
 
 
  0.752
fen
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (327 aa)
     
 
  0.704
Mvol_0356
TIGRFAM- exodeoxyribonuclease III Xth; exodeoxyribonuclease III; KEGG- hac-Hac_0003 exodeoxyribonuclease III; PFAM- Endonuclease/exonuclease/phosphatase (249 aa)
   
 
  0.686
Mvol_0936
ERCC4 domain protein; KEGG- hypothetical protein; K10896 fanconi anemia group M protein; PFAM- ERCC4 domain protein; helix-hairpin-helix motif; helicase domain protein; DEAD/DEAH box helicase domain protein; type III restriction protein res subunit; SMART- DEAD-like helicase; helicase domain protein (822 aa)
     
 
  0.683
Mvol_1508
KEGG- FHA domain protein (369 aa)
     
 
  0.670
Mvol_1013
PFAM- nucleic acid binding OB-fold tRNA/helicase-type; KEGG- hypothetical protein; K07466 replication factor A1 (643 aa)
     
 
  0.670
Mvol_1670
SMART- DNA-directed DNA polymerase B; TIGRFAM- DNA polymerase Pol2; KEGG- DNA polymerase delta catalytic subunit; K02327 DNA polymerase delta subunit 1; PFAM- DNA polymerase B region; DNA polymerase B exonuclease (879 aa)
     
 
  0.614
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (322 aa)
   
 
  0.597
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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