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taw2 protein (Methanococcus voltae) - STRING interaction network
"taw2" - tRNA(Phe) in Methanococcus voltae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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taw2tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) (258 aa)    
Predicted Functional Partners:
taw3
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 (195 aa)
   
  0.876
Mvol_1365
PFAM- NMD3 family protein; KEGG- nonsense-mediated mRNA decay protein; K07562 nonsense-mediated mRNA decay protein 3 (377 aa)
 
        0.749
prf1
Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (418 aa)
   
 
  0.738
taw1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) (345 aa)
 
   
  0.686
dphB
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis (255 aa)
 
        0.649
pus10
tRNA pseudouridine synthase Pus10; Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs (519 aa)
   
   
  0.607
Mvol_1562
PFAM- putative RNA methylase; THUMP domain protein; KEGG- TRMT11; tRNA methyltransferase 11 homolog (S. cerevisiae) (420 aa)
   
   
  0.581
eif2b
Translation initiation factor 2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (140 aa)
   
        0.568
rpl15e
PFAM- Ribosomal protein L15e; KEGG- hypothetical protein LOC100263573; Belongs to the eukaryotic ribosomal protein eL15 family (194 aa)
   
        0.559
rps4e
30S ribosomal protein S4e; KEGG- Hypothetical protein CBG05762; K02987 small subunit ribosomal protein S4e; PFAM- Ribosomal protein S4E, central domain protein; Ribosomal protein S4E domain protein; RNA-binding S4 domain protein; SMART- RNA-binding S4 domain protein; Belongs to the eukaryotic ribosomal protein eS4 family (244 aa)
   
        0.547
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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