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Mvol_0543 protein (Methanococcus voltae) - STRING interaction network
"Mvol_0543" - PFAM: UvrD/REP helicase in Methanococcus voltae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Mvol_0543PFAM- UvrD/REP helicase; KEGG- bab-bbp540 ATP-dependent DNA helicase Rep (1085 aa)    
Predicted Functional Partners:
Mvol_0544
TPR repeat-containing protein; KEGG- hhe-HH1443 putative endonuclease; PFAM- TPR repeat-containing protein; ATPase associated with various cellular activities AAA_5; Tetratricopeptide TPR_2 repeat protein; SMART- Tetratricopeptide repeat (890 aa)
   
 
  0.866
smc
Chromosome partition protein Smc; Required for chromosome condensation and partitioning; Belongs to the SMC family (1199 aa)
   
 
  0.815
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] (828 aa)
 
 
  0.732
rad50
DNA double-strand break repair Rad50 ATPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily (1113 aa)
   
 
  0.706
Mvol_0035
PFAM- SMC domain protein; KEGG- viral A-type inclusion protein (1113 aa)
   
 
  0.706
Mvol_1403
PFAM- TrkA-N domain protein; Ion transport 2 domain protein; KEGG- dde-Dde_2095 TrkA family potassium uptake protein (335 aa)
   
        0.688
Mvol_0972
Superfamily I DNA and RNA helicase-like protein; KEGG- rso-RS02993 hypothetical protein (713 aa)
              0.684
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (269 aa)
   
 
  0.666
Mvol_1027
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (888 aa)
 
 
  0.664
fen
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (327 aa)
   
 
  0.642
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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