STRINGSTRING
trpA protein (Methanococcus voltae) - STRING interaction network
"trpA" - Tryptophan synthase subunit alpha in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (270 aa)    
Predicted Functional Partners:
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (399 aa)
  0.999
Mvol_0580
Indole-3-glycerol-phosphate synthase (246 aa)
 
  0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (362 aa)
   
  0.994
Mvol_0578
Anthranilate synthase component I (478 aa)
 
 
  0.992
trpF
N-(5’phosphoribosyl)anthranilate isomerase (223 aa)
 
   
  0.988
Mvol_0577
Glutamine amidotransferase of anthranilate synthase (193 aa)
 
   
  0.961
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (242 aa)
         
  0.934
Mvol_0837
Phosphoserine phosphatase SerB (232 aa)
   
 
  0.920
Mvol_0778
Serine dehydratase subunit alpha (435 aa)
       
  0.907
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (184 aa)
           
  0.905
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
Server load: low (12%) [HD]