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mvk protein (Methanococcus voltae) - STRING interaction network
"mvk" - Mevalonate kinase in Methanococcus voltae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily (356 aa)    
Predicted Functional Partners:
Mvol_1440
TIGRFAM- 3-hydroxy-3-methylglutaryl Coenzyme A reductase; KEGG- hmgA; hmg CoA reductase A; K00021 3-hydroxy-3-methylglutaryl-CoA reductase; PFAM- hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family (429 aa)
 
 
  0.984
Mvol_1261
Isopentenyl phosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids (264 aa)
 
     
  0.977
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily (307 aa)
     
   
  0.922
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (353 aa)
 
     
  0.918
rps2
30S ribosomal protein S2; KEGG- hypothetical protein; K02998 small subunit ribosomal protein SAe; TIGRFAM- ribosomal protein S2; PFAM- ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family (218 aa)
 
     
  0.899
Mvol_1386
Dimethylallyltranstransferase; KEGG- dal-Dalk_3236 polyprenyl synthetase; PFAM- Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family (316 aa)
   
 
  0.881
Mvol_0985
MEMO1 family protein Mvol_0985; PFAM- protein of unknown function DUF52; KEGG- pca-Pcar_1651 dioxygenase; Belongs to the MEMO1 family (286 aa)
 
     
  0.879
carS
CDP-archaeol synthase; Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids (179 aa)
 
   
  0.864
Mvol_0622
KEGG- hypothetical protein; TIGRFAM- selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM- protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein (529 aa)
              0.858
Mvol_0283
UPF0219 protein Mvol_0283; KEGG- pfl-PFL_5954 hypothetical protein; TIGRFAM- hydroxymethylglutaryl-CoA synthase; PFAM- 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Hydroxymethylglutaryl-coenzyme A synthase domain; Belongs to the UPF0219 family (349 aa)
 
   
  0.852
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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