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cofG protein (Methanococcus voltae) - STRING interaction network
"cofG" - 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit in Methanococcus voltae
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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cofG7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (368 aa)    
Predicted Functional Partners:
cofH
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (355 aa)
   
  0.999
cofD
LPPG domain-containing protein containing protein; Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5’)guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP (341 aa)
 
 
  0.995
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (426 aa)
   
 
  0.959
Mvol_0888
F420-dependent oxidoreductase (257 aa)
 
   
  0.923
Mvol_1118
NADPH-dependent F420 reductase (231 aa)
 
     
  0.853
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (244 aa)
       
  0.842
mtd
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl- H(4)MPT(+) to methylene-H(4)MPT (277 aa)
         
  0.835
pgk2
ATP-cone domain-containing protein (311 aa)
     
   
  0.830
mtrC
Tetrahydromethanopterin S-methyltransferase subunit C; Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step (263 aa)
           
  0.830
mtrD
Tetrahydromethanopterin S-methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step (236 aa)
           
  0.830
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
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