node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvol_0328 | Mvol_0612 | Mvol_0328 | Mvol_0612 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | 0.977 |
Mvol_0328 | Mvol_1011 | Mvol_0328 | Mvol_1011 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | TIGRFAM- precorrin-3B C17-methyltransferase; KEGG- sea-SeAg_B2149 precorrin-3B C17-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | 0.977 |
Mvol_0328 | Mvol_1167 | Mvol_0328 | Mvol_1167 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | PFAM- cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG- dal-Dalk_0451 cobalamin (vitamin B12) biosynthesis CbiG protein | 0.828 |
Mvol_0328 | Mvol_1302 | Mvol_0328 | Mvol_1302 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | TIGRFAM- precorrin-4 C11-methyltransferase; KEGG- gur-Gura_0039 precorrin-4 C11-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | 0.722 |
Mvol_0328 | Mvol_1633 | Mvol_0328 | Mvol_1633 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | PFAM- Precorrin-8X methylmutase CbiC/CobH; KEGG- sse-Ssed_2081 precorrin-8X methylmutase | 0.755 |
Mvol_0328 | Mvol_1712 | Mvol_0328 | Mvol_1712 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | KEGG- gme-Gmet_0482 precorrin-2 C20-methyltransferase / cobalt-factor II C20-methyltransferase; TIGRFAM- precorrin-2 C20-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | 0.867 |
Mvol_0328 | cbiA | Mvol_0328 | Mvol_1625 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source | 0.860 |
Mvol_0328 | cbiD | Mvol_0328 | Mvol_1673 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | Cobalt-precorrin-5B C(1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A | 0.976 |
Mvol_0328 | cbiT | Mvol_0328 | Mvol_0848 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 | 0.998 |
Mvol_0328 | cbiX | Mvol_0328 | Mvol_1554 | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin | 0.676 |
Mvol_0612 | Mvol_0328 | Mvol_0612 | Mvol_0328 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | Precorrin-6x reductase; KEGG- rso-RSp0618 bifunctional- precorrin-3 methyltransferase/precorrin-6X reductase oxidoreductase protein; TIGRFAM- precorrin-6x reductase; PFAM- Precorrin-6x reductase CbiJ/CobK | 0.977 |
Mvol_0612 | Mvol_1011 | Mvol_0612 | Mvol_1011 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | TIGRFAM- precorrin-3B C17-methyltransferase; KEGG- sea-SeAg_B2149 precorrin-3B C17-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | 0.863 |
Mvol_0612 | Mvol_1167 | Mvol_0612 | Mvol_1167 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | PFAM- cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG- dal-Dalk_0451 cobalamin (vitamin B12) biosynthesis CbiG protein | 0.886 |
Mvol_0612 | Mvol_1302 | Mvol_0612 | Mvol_1302 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | TIGRFAM- precorrin-4 C11-methyltransferase; KEGG- gur-Gura_0039 precorrin-4 C11-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | 0.906 |
Mvol_0612 | Mvol_1633 | Mvol_0612 | Mvol_1633 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | PFAM- Precorrin-8X methylmutase CbiC/CobH; KEGG- sse-Ssed_2081 precorrin-8X methylmutase | 0.991 |
Mvol_0612 | Mvol_1712 | Mvol_0612 | Mvol_1712 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | KEGG- gme-Gmet_0482 precorrin-2 C20-methyltransferase / cobalt-factor II C20-methyltransferase; TIGRFAM- precorrin-2 C20-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | 0.929 |
Mvol_0612 | cbiA | Mvol_0612 | Mvol_1625 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source | 0.885 |
Mvol_0612 | cbiD | Mvol_0612 | Mvol_1673 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | Cobalt-precorrin-5B C(1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A | 0.883 |
Mvol_0612 | cbiT | Mvol_0612 | Mvol_0848 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 | 0.998 |
Mvol_0612 | cbiX | Mvol_0612 | Mvol_1554 | KEGG- yen-YE2721 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM- precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase | Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin | 0.844 |