node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvol_0242 | Mvol_0744 | Mvol_0242 | Mvol_0744 | PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: mxa:MXAN_3507 UDP-glucose 4-epimerase. | PFAM: glycosyl transferase family 2; KEGG: nis:NIS_1251 glycosyl transferase. | 0.619 |
Mvol_0242 | pyrD | Mvol_0242 | Mvol_1191 | PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: mxa:MXAN_3507 UDP-glucose 4-epimerase. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.426 |
Mvol_0242 | ribH | Mvol_0242 | Mvol_1381 | PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: mxa:MXAN_3507 UDP-glucose 4-epimerase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.430 |
Mvol_0242 | ribL | Mvol_0242 | Mvol_0889 | PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: mxa:MXAN_3507 UDP-glucose 4-epimerase. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.472 |
Mvol_0744 | Mvol_0242 | Mvol_0744 | Mvol_0242 | PFAM: glycosyl transferase family 2; KEGG: nis:NIS_1251 glycosyl transferase. | PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: mxa:MXAN_3507 UDP-glucose 4-epimerase. | 0.619 |
Mvol_0744 | ribL | Mvol_0744 | Mvol_0889 | PFAM: glycosyl transferase family 2; KEGG: nis:NIS_1251 glycosyl transferase. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.426 |
Mvol_0888 | ribL | Mvol_0888 | Mvol_0889 | F420-dependent oxidoreductase; KEGG: eba:p2A347 hypothetical protein; TIGRFAM: F420-dependent oxidoreductase; PFAM: protein of unknown function DUF129. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.440 |
Mvol_1111 | ribK | Mvol_1111 | Mvol_1472 | PFAM: Translin; KEGG: translin-associated protein X. | Protein of unknown function DUF120; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.690 |
Mvol_1111 | ribL | Mvol_1111 | Mvol_0889 | PFAM: Translin; KEGG: translin-associated protein X. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.656 |
Mvol_1692 | ribH | Mvol_1692 | Mvol_1381 | PFAM: aminotransferase class V; KEGG: ank:AnaeK_3093 aminotransferase class V. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.469 |
Mvol_1692 | ribL | Mvol_1692 | Mvol_0889 | PFAM: aminotransferase class V; KEGG: ank:AnaeK_3093 aminotransferase class V. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.602 |
pyrD | Mvol_0242 | Mvol_1191 | Mvol_0242 | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: mxa:MXAN_3507 UDP-glucose 4-epimerase. | 0.426 |
pyrD | ribH | Mvol_1191 | Mvol_1381 | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.895 |
pyrD | ribL | Mvol_1191 | Mvol_0889 | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.735 |
ribH | Mvol_0242 | Mvol_1381 | Mvol_0242 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: mxa:MXAN_3507 UDP-glucose 4-epimerase. | 0.430 |
ribH | Mvol_1692 | Mvol_1381 | Mvol_1692 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | PFAM: aminotransferase class V; KEGG: ank:AnaeK_3093 aminotransferase class V. | 0.469 |
ribH | pyrD | Mvol_1381 | Mvol_1191 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. | 0.895 |
ribH | ribL | Mvol_1381 | Mvol_0889 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.707 |
ribK | Mvol_1111 | Mvol_1472 | Mvol_1111 | Protein of unknown function DUF120; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | PFAM: Translin; KEGG: translin-associated protein X. | 0.690 |
ribK | ribL | Mvol_1472 | Mvol_0889 | Protein of unknown function DUF120; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.983 |