STRINGSTRING
pyrK protein (Methanococcus voltae) - STRING interaction network
"pyrK" - Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding domain-containing protein in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrKDihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding domain-containing protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+) (260 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate (319 aa)
  0.999
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (184 aa)
       
  0.970
Mvol_0788
Dihydroorotase, multifunctional complex type (476 aa)
   
 
  0.962
Mvol_0808
CoB/CoM heterodisulfide reductase subunit B (306 aa)
     
 
  0.918
Mvol_0794
CoB/CoM heterodisulfide reductase subunit B (294 aa)
     
 
  0.918
Mvol_1264
Methyl-viologen-reducing hydrogenase subunit delta (107 aa)
     
      0.917
Mvol_0586
Methyl-viologen-reducing hydrogenase subunit delta (155 aa)
     
      0.917
Mvol_1263
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (659 aa)
     
 
  0.877
Mvol_0582
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein (654 aa)
     
 
  0.877
Mvol_0818
Coenzyme F420 hydrogenase/dehydrogenase subunit beta domain-containing protein (386 aa)
   
 
  0.860
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
Server load: low (20%) [HD]