• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
rtcB protein (Methanococcus voltae) - STRING interaction network
"rtcB" - tRNA-splicing ligase RtcB in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rtcBtRNA-splicing ligase RtcB; PFAM- protein of unknown function UPF0027; KEGG- sat-SYN_02046 RtcB protein; Belongs to the RtcB family (480 aa)    
Predicted Functional Partners:
Mvol_1194
PFAM- CoA-binding domain protein; KEGG- dat-HRM2_16770 SucD3 (707 aa)
     
      0.992
Mvol_1635
Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function; In the C-terminal section; belongs to the protein ki [...] (575 aa)
         
  0.937
Mvol_0779
PFAM- protein of unknown function DUF101; KEGG- AGAP001976-PA (156 aa)
 
 
  0.906
eif1a
Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (104 aa)
         
  0.849
cbiA
Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source (459 aa)
           
  0.711
Mvol_0151
RIO-like kinase; KEGG- hypothetical protein; K07178 RIO kinase 1; PFAM- RIO-like kinase; SMART- protein of unknown function RIO1 (297 aa)
   
   
  0.695
top6A
Type 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family (365 aa)
 
          0.661
Mvol_0392
KEGG- nam-NAMH_1393 phosphoglucosamine mutase; PFAM- phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; Belongs to the phosphohexose mutase family (458 aa)
   
   
  0.647
Mvol_1426
RIO-like kinase; KEGG- predicted protein; K07179 RIO kinase 2; PFAM- RIO-like kinase; RIO2 kinase, winged helix domain protein; SMART- protein of unknown function RIO1 (295 aa)
     
   
  0.643
Mvol_1511
KEGG- erg-ERGA_CDS_02520 biotin-protein ligase; TIGRFAM- biotin/acetyl-CoA-carboxylase ligase; PFAM- biotin/lipoate A/B protein ligase (275 aa)
              0.643
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
Server load: low (13%) [HD]