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thyA protein (Methanococcus voltae) - STRING interaction network
"thyA" - Thymidylate synthase, methanogen type in Methanococcus voltae
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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thyAThymidylate synthase, methanogen type; May catalyze the biosynthesis of dTMP using an unknown cosubstrate (213 aa)    
Predicted Functional Partners:
pcn
Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (269 aa)
     
 
  0.963
tmk
Thymidylate kinase (223 aa)
   
  0.955
dcd
Deoxycytidine triphosphate deaminase (201 aa)
       
  0.919
Mvol_0657
dUTP diphosphatase (155 aa)
       
  0.919
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates (269 aa)
   
 
    0.906
priS
DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (369 aa)
     
   
  0.882
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] (828 aa)
   
 
  0.818
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (703 aa)
   
   
  0.767
Mvol_1334
Inosine-5’-monophosphate dehydrogenase (498 aa)
   
   
  0.764
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (283 aa)
   
   
  0.749
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
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