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tmk protein (Methanococcus voltae) - STRING interaction network
"tmk" - Thymidylate kinase in Methanococcus voltae
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
tmkThymidylate kinase (223 aa)    
Predicted Functional Partners:
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates (269 aa)
   
    0.993
thyA
Thymidylate synthase, methanogen type; May catalyze the biosynthesis of dTMP using an unknown cosubstrate (213 aa)
   
  0.955
dcd
Deoxycytidine triphosphate deaminase (201 aa)
       
  0.928
Mvol_0657
dUTP diphosphatase (155 aa)
       
  0.928
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (134 aa)
   
 
  0.928
Mvol_1334
Inosine-5’-monophosphate dehydrogenase (498 aa)
   
   
  0.902
rfcL
AAA ATPase central domain-containing protein; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA (510 aa)
   
 
  0.883
rfcS
Replication factor C; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA (314 aa)
   
 
  0.883
tfe
Transcription factor TFIIE subunit alpha; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation [...] (183 aa)
     
   
  0.816
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] (828 aa)
 
   
  0.815
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
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