STRINGSTRING
tuf protein (Methanococcus voltae) - STRING interaction network
"tuf" - Translation elongation factor EF-1 subunit alpha in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tufTranslation elongation factor EF-1 subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (428 aa)    
Predicted Functional Partners:
prf1
eRF1 domain 2 protein; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (418 aa)
   
  0.999
rps10
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes (102 aa)
   
    0.996
rps3ae
30S ribosomal protein S3Ae (218 aa)
   
  0.993
ef1b
Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA (89 aa)
     
  0.992
rps6e
30S ribosomal protein S6e (124 aa)
   
  0.992
rps2
30S ribosomal protein S2 (218 aa)
 
  0.992
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (727 aa)
 
  0.991
pelA
Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity (348 aa)
     
  0.990
Mvol_0393
50S ribosomal protein L7Ae/L30e/S12e/Gadd45 (117 aa)
 
  0.989
rps19p
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (160 aa)
   
  0.989
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
Server load: low (17%) [HD]