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secY protein (Methanococcus voltae) - STRING interaction network
"secY" - Preprotein translocase subunit SecY in Methanococcus voltae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (446 aa)    
Predicted Functional Partners:
rpl24p
50S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit (119 aa)
   
  0.999
Mvol_1114
50S ribosomal protein L23 (86 aa)
   
  0.999
rpl5
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (181 aa)
 
  0.999
rpl22
50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (154 aa)
   
  0.997
rpl14
50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (132 aa)
   
  0.995
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel (253 aa)
 
  0.994
rpl18
50S ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (194 aa)
 
  0.993
rpl1
50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release (213 aa)
   
  0.992
rps5
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy (221 aa)
   
 
  0.992
rps3
30S ribosomal protein S3; Binds the lower part of the 30S subunit head (218 aa)
 
 
  0.991
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
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