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pyrE protein (Methanococcus voltae) - STRING interaction network
"pyrE" - Orotate phosphoribosyltransferase in Methanococcus voltae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (184 aa)    
Predicted Functional Partners:
Mvol_0759
KEGG- nam-NAMH_0054 orotidine 5’-phosphate decarboxylase; TIGRFAM- orotidine 5’-phosphate decarboxylase; PFAM- Orotidine 5’-phosphate decarboxylase; Belongs to the OMP decarboxylase family (217 aa)
   
 
  0.999
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate (319 aa)
 
 
  0.988
carA
KEGG- sfu-Sfum_0009 carbamoyl phosphate synthase small subunit; TIGRFAM- carbamoyl-phosphate synthase, small subunit; PFAM- Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; Belongs to the CarA family (366 aa)
 
   
  0.977
purD
TIGRFAM- phosphoribosylamine/glycine ligase; KEGG- sat-SYN_02439 phosphoribosylamine--glycine ligase; PFAM- Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family (445 aa)
   
   
  0.970
pyrK
Probable dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+) (260 aa)
       
  0.970
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) (287 aa)
   
 
  0.930
Mvol_0788
KEGG- bba-Bd2688 dihydroorotase; TIGRFAM- dihydroorotase, multifunctional complex type; PFAM- amidohydrolase (476 aa)
 
   
  0.898
pyrB
TIGRFAM- aspartate carbamoyltransferase; KEGG- vvu-VV1_1465 aspartate carbamoyltransferase catalytic subunit; PFAM- aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region (302 aa)
   
   
  0.898
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate; Belongs to the TrpA family (270 aa)
         
  0.841
carS
CDP-archaeol synthase; Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids (179 aa)
 
   
  0.736
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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