• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
bioD protein (Methanococcus voltae) - STRING interaction network
"bioD" - ATP-dependent dethiobiotin synthetase BioD in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioDATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (217 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family (354 aa)
 
  0.999
Mvol_0761
PFAM- aminotransferase class-III; KEGG- gsu-GSU1582 adenosylmethionine--8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family (516 aa)
 
  0.996
Mvol_1348
KEGG- dat-HRM2_15240 BioB2; PFAM- Radical SAM domain protein; SMART- Elongator protein 3/MiaB/NifB (382 aa)
 
 
  0.990
Mvol_1144
KEGG- gbm-Gbem_0831 8-amino-7-oxononanoate synthase; PFAM- aminotransferase class I and II (397 aa)
   
  0.957
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components- the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family (278 aa)
         
  0.864
Mvol_1143
KEGG- pca-Pcar_1666 6-carboxyhexanoate--CoA ligase (270 aa)
 
     
  0.806
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (127 aa)
         
  0.641
Mvol_0130
Peptidyl-prolyl cis-trans isomerase; PFAM- peptidylprolyl isomerase FKBP-type; KEGG- acb-A1S_0018 FKBP-type peptidyl-prolyl cis-trans isomerase (228 aa)
   
   
  0.636
Mvol_1414
KEGG- dat-HRM2_15240 BioB2; PFAM- Radical SAM domain protein; SMART- Elongator protein 3/MiaB/NifB (360 aa)
   
   
  0.566
Mvol_1511
KEGG- erg-ERGA_CDS_02520 biotin-protein ligase; TIGRFAM- biotin/acetyl-CoA-carboxylase ligase; PFAM- biotin/lipoate A/B protein ligase (275 aa)
   
   
  0.525
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
Server load: low (11%) [HD]