• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
Mvol_1222 protein (Methanococcus voltae) - STRING interaction network
"Mvol_1222" - TIGRFAM: metal dependent phophohydrolase in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mvol_1222TIGRFAM- metal dependent phophohydrolase; PFAM- metal-dependent phosphohydrolase HD sub domain; KEGG- ank-AnaeK_2543 metal dependent phosphohydrolase; SMART- metal-dependent phosphohydrolase HD region (287 aa)    
Predicted Functional Partners:
mptA
GTP cyclohydrolase MptA; Converts GTP to 7,8-dihydro-D-neopterin 2’,3’-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin (311 aa)
 
   
  0.969
Mvol_1471
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (232 aa)
         
  0.694
rad50
DNA double-strand break repair Rad50 ATPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily (1113 aa)
         
  0.684
Mvol_0035
PFAM- SMC domain protein; KEGG- viral A-type inclusion protein (1113 aa)
         
  0.684
Mvol_1223
PFAM- 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG- abu-Abu_0354 ferredoxin-type protein NapF (228 aa)
              0.652
mptD
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family (123 aa)
           
  0.650
trpF
PFAM- N-(5’phosphoribosyl)anthranilate isomerase (PRAI); KEGG- mes-Meso_0667 N-(5’-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family (223 aa)
         
  0.638
mptE
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family (249 aa)
           
  0.632
Mvol_0043
PFAM- protein of unknown function DUF115; KEGG- conserved hypothetical protein (249 aa)
           
  0.632
Mvol_0888
F420-dependent oxidoreductase; KEGG- eba-p2A347 hypothetical protein; TIGRFAM- F420-dependent oxidoreductase; PFAM- protein of unknown function DUF129 (257 aa)
           
  0.607
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
Server load: low (7%) [HD]