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Mvol_1254 protein (Methanococcus voltae) - STRING interaction network
"Mvol_1254" - KEGG: ech:ECH_0914 phosphomethylpyrimidine kinase in Methanococcus voltae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Mvol_1254KEGG- ech-ECH_0914 phosphomethylpyrimidine kinase; PFAM- Phosphomethylpyrimidine kinase type-1; Phosphomethylpyrimidine kinase (558 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP); Belongs to the thiamine-phosphate synthase family (206 aa)
 
  0.999
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family (269 aa)
 
  0.995
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction; Belongs to the ThiC family (426 aa)
 
  0.994
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family (370 aa)
 
 
  0.994
thi4
Thiamine thiazole synthase; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur; Belongs to the THI4 family (266 aa)
 
   
  0.960
moaA
Probable GTP 3’,8-cyclase; Catalyzes the cyclization of GTP to (8S)-3’,8-cyclo-7,8- dihydroguanosine 5’-triphosphate; Belongs to the radical SAM superfamily. MoaA family (298 aa)
         
  0.835
dapB
4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (271 aa)
         
  0.766
Mvol_0641
PFAM- thiamineS protein (64 aa)
   
   
  0.760
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (338 aa)
         
  0.729
dapA
4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (288 aa)
         
  0.696
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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