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guaB protein (Methanococcus voltae) - STRING interaction network
"guaB" - Inosine-5'-monophosphate dehydrogenase in Methanococcus voltae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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guaBInosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (498 aa)    
Predicted Functional Partners:
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (338 aa)
 
 
  0.999
guaAB
GMP synthase [glutamine-hydrolyzing] subunit B; Catalyzes the synthesis of GMP from XMP (310 aa)
 
  0.998
guaAA
GMP synthase [glutamine-hydrolyzing] subunit A; Catalyzes the synthesis of GMP from XMP (188 aa)
 
  0.992
Mvol_0040
TIGRFAM- GMP synthase, large subunit; KEGG- gem-GM21_0782 GMP synthase, large subunit; PFAM- GMP synthase domain protein (310 aa)
 
 
  0.986
Mvol_1457
KEGG- hypothetical protein; TIGRFAM- non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM- Ham1 family protein; Belongs to the HAM1 NTPase family (196 aa)
   
  0.970
Mvol_1641
PFAM- PfkB domain protein; KEGG- hha-Hhal_1195 ribokinase-like domain-containing protein; Belongs to the carbohydrate kinase PfkB family (316 aa)
   
 
  0.932
purO
IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP (209 aa)
 
   
  0.932
surE
5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family (269 aa)
 
 
    0.925
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates (537 aa)
   
 
  0.914
Mvol_0041
TIGRFAM- CTP synthase; KEGG- sat-SYN_02922 CTP synthetase; PFAM- CTP synthase-like; glutamine amidotransferase class-I (537 aa)
   
 
  0.914
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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