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hisE protein (Methanococcus voltae) - STRING interaction network
"hisE" - phosphoribosyl-ATP diphosphatase in Methanococcus voltae
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisEphosphoribosyl-ATP diphosphatase (100 aa)    
Predicted Functional Partners:
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (127 aa)
     
  0.999
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (293 aa)
   
 
  0.996
hisC
Histidinol-phosphate aminotransferase (370 aa)
   
   
  0.985
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (283 aa)
   
   
  0.977
Mvol_1693
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (213 aa)
   
   
  0.961
Mvol_0235
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (231 aa)
   
   
  0.961
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (425 aa)
   
   
  0.956
hisB
Imidazoleglycerol-phosphate dehydratase (190 aa)
   
   
  0.953
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (242 aa)
   
   
  0.941
Mvol_0236
Histidine biosynthesis protein (251 aa)
   
   
  0.916
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
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