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ribH protein (Methanococcus voltae) - STRING interaction network
"ribH" - 6,7-dimethyl-8-ribityllumazine synthase in Methanococcus voltae
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family (138 aa)    
Predicted Functional Partners:
Mvol_1471
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (232 aa)
 
 
  0.999
Mvol_1470
TIGRFAM- riboflavin synthase; PFAM- 67-dimethyl-8-ribityllumazine synthase (160 aa)
 
   
  0.997
Mvol_0148
TIGRFAM- 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase; KEGG- apl-APL_0382 riboflavin biosynthesis protein; PFAM- bifunctional deaminase-reductase domain protein (235 aa)
 
 
  0.976
ribK
Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family (133 aa)
         
  0.913
ribL
FAD synthase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme (174 aa)
         
  0.853
hisE
KEGG- gem-GM21_3794 phosphoribosyl-ATP diphosphatase; TIGRFAM- phosphoribosyl-ATP diphosphatase; PFAM- phosphoribosyl-ATP pyrophosphohydrolase (100 aa)
              0.827
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate (319 aa)
   
   
  0.826
mptA
GTP cyclohydrolase MptA; Converts GTP to 7,8-dihydro-D-neopterin 2’,3’-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin (311 aa)
           
  0.772
purE
N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (156 aa)
   
   
  0.755
hemC
Probable porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (316 aa)
   
   
  0.705
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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