• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
tfb protein (Methanococcus voltae) - STRING interaction network
"tfb" - Transcription initiation factor IIB in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tfbTranscription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) (337 aa)    
Predicted Functional Partners:
tbp
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (181 aa)
 
 
  0.999
Mvol_1070
TIGRFAM- transcription factor S; PFAM- Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; KEGG- DNA-directed RNA polymerase III family protein; SMART- Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family (105 aa)
   
 
  0.993
Mvol_0222
PFAM- RNA polymerase Rpb6; KEGG- hypothetical protein; K03014 DNA-directed RNA Polymerase II subunit F (70 aa)
   
 
  0.974
tfe
Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...] (183 aa)
   
 
  0.972
Mvol_0217
RNA polymerase insert; KEGG- hypothetical protein; K03027 DNA-directed RNA Polymerase III subunit C5; PFAM- RNA polymerase insert; RNA polymerase dimerisation; SMART- RNA polymerase RpoA/D/Rpb3-type (188 aa)
   
 
  0.965
Mvol_1207
SMART- RNA polymerase Rbp10 (46 aa)
   
 
  0.959
Mvol_0221
PFAM- RNA polymerase, N/8 Kd subunit; KEGG- DNA-directed RNA polymerase II 8.2 kDa polypeptide; K03007 DNA-directed RNA Polymerase II subunit L (68 aa)
     
 
  0.957
Mvol_0001
TIGRFAM- DNA-directed RNA polymerase; KEGG- hypothetical protein; K03022 DNA-directed RNA polymerase III subunit C25; PFAM- RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein (189 aa)
   
 
  0.943
rpoA2
DNA-directed RNA polymerase subunit A’’; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (387 aa)
   
 
  0.943
Mvol_1700
PFAM- RNA polymerase dimerisation; KEGG- predicted protein; K03020 DNA-directed RNA polymerase III subunit C19 (94 aa)
     
 
  0.941
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
Server load: low (11%) [HD]