STRINGSTRING
pelA protein (Methanococcus voltae) - STRING interaction network
"pelA" - Translation factor pelota in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pelATranslation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity (348 aa)    
Predicted Functional Partners:
tuf
Translation elongation factor EF-1 subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (428 aa)
     
  0.990
Mvol_1672
ABC transporter-like protein (590 aa)
 
 
  0.902
Mvol_1427
DNA binding protein, Tfx family; Putative transcriptional regulator (146 aa)
 
          0.824
Mvol_1000
Fibronectin-binding A domain-containing protein (722 aa)
 
     
  0.815
rpl10
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (336 aa)
   
      0.757
rps6e
30S ribosomal protein S6e (124 aa)
     
 
  0.744
tfb
Transcription factor TFIIB cyclin-like protein; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) (337 aa)
 
     
  0.678
rpl11
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors (159 aa)
       
      0.642
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (78 aa)
 
          0.616
Mvol_0064
Phosphoesterase RecJ domain-containing protein (757 aa)
 
          0.594
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
Server load: low (6%) [HD]