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hemA protein (Methanococcus voltae) - STRING interaction network
"hemA" - Glutamyl-tRNA reductase in Methanococcus voltae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA); Belongs to the glutamyl-tRNA reductase family (417 aa)    
Predicted Functional Partners:
hemL
KEGG- pau-PA14_12390 glutamate-1-semialdehyde aminotransferase; TIGRFAM- glutamate-1-semialdehyde-2,1-aminomutase; PFAM- aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily (427 aa)
 
  0.998
hemC
Probable porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (316 aa)
   
  0.995
gltX
Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction- glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (574 aa)
   
 
  0.983
Mvol_1442
TIGRFAM- siroheme synthase; KEGG- sun-SUN_0295 hypothetical protein (239 aa)
   
   
  0.980
Mvol_0833
KEGG- sfu-Sfum_3057 delta-aminolevulinic acid dehydratase; PFAM- delta-aminolevulinic acid dehydratase; Belongs to the ALAD family (325 aa)
 
   
  0.962
Mvol_0643
KEGG- dal-Dalk_4009 uroporphyrin-III C-methyltransferase; TIGRFAM- uroporphyrin-III C-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family (247 aa)
   
 
  0.933
Mvol_1661
PFAM- Uroporphyrinogen III synthase HEM4; KEGG- lip-LI0117 siroheme synthase (242 aa)
 
 
  0.911
Mvol_1440
TIGRFAM- 3-hydroxy-3-methylglutaryl Coenzyme A reductase; KEGG- hmgA; hmg CoA reductase A; K00021 3-hydroxy-3-methylglutaryl-CoA reductase; PFAM- hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family (429 aa)
         
  0.855
cbiA
Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source (459 aa)
   
   
  0.760
cobS
Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5’-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5’-phosphate; Belongs to the CobS family (260 aa)
         
  0.751
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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