• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
hemL protein (Methanococcus voltae) - STRING interaction network
"hemL" - KEGG: pau:PA14_12390 glutamate-1-semialdehyde aminotransferase in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLKEGG- pau-PA14_12390 glutamate-1-semialdehyde aminotransferase; TIGRFAM- glutamate-1-semialdehyde-2,1-aminomutase; PFAM- aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily (427 aa)    
Predicted Functional Partners:
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA); Belongs to the glutamyl-tRNA reductase family (417 aa)
 
  0.998
Mvol_0833
KEGG- sfu-Sfum_3057 delta-aminolevulinic acid dehydratase; PFAM- delta-aminolevulinic acid dehydratase; Belongs to the ALAD family (325 aa)
 
 
  0.995
hemC
Probable porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (316 aa)
 
   
  0.970
Mvol_1661
PFAM- Uroporphyrinogen III synthase HEM4; KEGG- lip-LI0117 siroheme synthase (242 aa)
 
 
  0.939
Mvol_0643
KEGG- dal-Dalk_4009 uroporphyrin-III C-methyltransferase; TIGRFAM- uroporphyrin-III C-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family (247 aa)
   
 
  0.932
Mvol_1442
TIGRFAM- siroheme synthase; KEGG- sun-SUN_0295 hypothetical protein (239 aa)
   
   
  0.863
gltX
Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction- glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (574 aa)
   
   
  0.850
Mvol_1463
annotation not available (91 aa)
              0.817
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP); Belongs to the thiamine-phosphate synthase family (206 aa)
 
   
  0.775
Mvol_1462
annotation not available (80 aa)
              0.771
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
Server load: low (9%) [HD]