Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
tRNA (guanine(26)-N(2))-dimethyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups (376 aa)
Predicted Functional Partners:
tRNA-guanine(15) transglycosylase; Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family (675 aa)
KEGG- hypothetical protein; TIGRFAM- small GTP-binding protein; PFAM- GTP-binding protein HSR1-related; Nucleolar GTP-binding-1 domain protein; Miro domain protein (354 aa)
SMART- Elongator protein 3/MiaB/NifB; TIGRFAM- histone acetyltransferase, ELP3 family; KEGG- histone acetyltransferase gcn5-type hat; K07739 elongator complex protein 3; PFAM- Radical SAM domain protein; GCN5-related N-acetyltransferase (553 aa)
Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2’-O position of the ribose in the fully assembled 50S ribosomal subunit (298 aa)
tRNA pseudouridine synthase Pus10; Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs (519 aa)
Hydrolase of the HD superfamily (Permuted catalytic motifs)-like protein; KEGG- sat-SYN_02251 HD superfamily hydrolase (585 aa)
Your Current Organism:
NCBI taxonomy Id: 456320 Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3