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guaAA protein (Methanococcus voltae) - STRING interaction network
"guaAA" - GMP synthase [glutamine-hydrolyzing] subunit A in Methanococcus voltae
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query proteins and first shell of interactors
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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guaAAGMP synthase [glutamine-hydrolyzing] subunit A; Catalyzes the synthesis of GMP from XMP (188 aa)    
Predicted Functional Partners:
guaAB
GMP synthase [glutamine-hydrolyzing] subunit B; Catalyzes the synthesis of GMP from XMP (310 aa)
   
  0.994
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (498 aa)
 
  0.992
Mvol_0040
TIGRFAM- GMP synthase, large subunit; KEGG- gem-GM21_0782 GMP synthase, large subunit; PFAM- GMP synthase domain protein (310 aa)
     
  0.972
hpt
Hypoxanthine/guanine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis; Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily (187 aa)
   
 
  0.934
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (176 aa)
   
 
  0.934
Mvol_1641
PFAM- PfkB domain protein; KEGG- hha-Hhal_1195 ribokinase-like domain-containing protein; Belongs to the carbohydrate kinase PfkB family (316 aa)
       
  0.927
Mvol_1457
KEGG- hypothetical protein; TIGRFAM- non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM- Ham1 family protein; Belongs to the HAM1 NTPase family (196 aa)
   
 
  0.918
surE
5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family (269 aa)
   
 
    0.910
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (478 aa)
     
  0.883
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (362 aa)
 
   
  0.847
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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