STRINGSTRING
hpt protein (Methanococcus voltae) - STRING interaction network
"hpt" - Phosphoribosyltransferase in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hptPhosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis (187 aa)    
Predicted Functional Partners:
Mvol_1664
Adenylosuccinate lyase (448 aa)
   
  0.982
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates (269 aa)
   
 
  0.963
guaAA
GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP (188 aa)
   
  0.962
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP (310 aa)
   
  0.961
Mvol_0040
GMP synthase, large subunit (310 aa)
   
  0.961
Mvol_1103
Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates (203 aa)
     
 
    0.905
purP
IMP biosynthesis enzyme PurP domain-containing protein; Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5’- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5’-monophosphate (FAICAR) in the absence of folates (361 aa)
       
    0.903
adkA
Adenylate kinase (192 aa)
         
  0.902
Mvol_1334
Inosine-5’-monophosphate dehydrogenase (498 aa)
   
 
  0.844
Mvol_1693
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (213 aa)
       
  0.819
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae, M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3, Methanococcus voltaei
Server load: low (23%) [HD]