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Mvol_1635 protein (Methanococcus voltae) - STRING interaction network
"Mvol_1635" - Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein in Methanococcus voltae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Mvol_1635Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function; In the C-terminal section; belongs to the protein ki [...] (575 aa)    
Predicted Functional Partners:
Mvol_0160
PFAM- Protein of unknown function DUF509 (172 aa)
       
 
  0.999
Mvol_0151
RIO-like kinase; KEGG- hypothetical protein; K07178 RIO kinase 1; PFAM- RIO-like kinase; SMART- protein of unknown function RIO1 (297 aa)
 
   
  0.999
Mvol_1426
RIO-like kinase; KEGG- predicted protein; K07179 RIO kinase 2; PFAM- RIO-like kinase; RIO2 kinase, winged helix domain protein; SMART- protein of unknown function RIO1 (295 aa)
     
   
  0.999
eif1a
Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (104 aa)
 
   
  0.956
Mvol_1474
KEGG- ppd-Ppro_1789 SUA5/YciO/YrdC/YwlC family protein; TIGRFAM- Sua5/YciO/YrdC/YwlC family protein; PFAM- SUA5/yciO/yrdC domain (209 aa)
 
   
  0.949
rtcB
tRNA-splicing ligase RtcB; PFAM- protein of unknown function UPF0027; KEGG- sat-SYN_02046 RtcB protein; Belongs to the RtcB family (480 aa)
         
  0.937
dnaG
DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication (603 aa)
   
 
  0.936
Mvol_0034
KEGG- retinitis pigmentosa GTPase regulator-like protein; PFAM- TOPRIM domain protein; SMART- Toprim sub domain protein (603 aa)
   
 
  0.936
fen
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (327 aa)
 
   
  0.930
hjc
Holliday junction resolvase Hjc; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5’-terminal phosphate and a 3’-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family (132 aa)
         
  0.925
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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