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aroA protein (Methanococcus voltae) - STRING interaction network
"aroA" - 3-phosphoshikimate 1-carboxyvinyltransferase in Methanococcus voltae
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate (456 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (388 aa)
 
 
  0.998
aroE
Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) (346 aa)
   
  0.995
aroK
TIGRFAM- shikimate kinase; KEGG- pat-Patl_3579 homoserine kinase; PFAM- GHMP kinase; GHMP kinase domain protein (303 aa)
 
   
    0.970
Mvol_1180
PFAM- Prephenate dehydrogenase; KEGG- hsm-HSM_1080 bifunctional chorismate mutase/prephenate dehydrogenase (393 aa)
   
  0.902
aroB'
3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis (374 aa)
 
 
 
  0.841
Mvol_1097
Prephenate dehydratase; KEGG- mmb-Mmol_0991 chorismate mutase; PFAM- prephenate dehydratase; amino acid-binding ACT domain protein (288 aa)
 
   
  0.834
aroD
3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate; Belongs to the type-I 3-dehydroquinase family (246 aa)
 
   
  0.773
Mvol_0138
PFAM- Chorismate mutase; KEGG- nis-NIS_0982 chorismate mutase (109 aa)
   
   
  0.711
Mvol_1666
KEGG- dps-DP0126 Xaa-Pro dipeptidase; PFAM- peptidase M24; Belongs to the peptidase M24B family (346 aa)
              0.696
Mvol_0862
Aspartokinase; TIGRFAM- aspartate kinase; aspartate kinase, monofunctional class; KEGG- mxa-MXAN_2278 aspartate kinase/homoserine dehydrogenase; PFAM- aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family (478 aa)
 
   
  0.692
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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