• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
Mvol_1689 protein (Methanococcus voltae) - STRING interaction network
"Mvol_1689" - Digeranylgeranylglycerophospholipid reductase in Methanococcus voltae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mvol_1689Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains (391 aa)    
Predicted Functional Partners:
Mvol_1278
Digeranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids (280 aa)
 
 
  0.951
carS
CDP-archaeol synthase; Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids (179 aa)
 
   
  0.934
Mvol_1690
PFAM- 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG- dat-HRM2_49340 PflC2 (54 aa)
              0.845
Mvol_1261
Isopentenyl phosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids (264 aa)
   
     
  0.734
Mvol_1386
Dimethylallyltranstransferase; KEGG- dal-Dalk_3236 polyprenyl synthetase; PFAM- Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family (316 aa)
 
 
  0.647
Mvol_0679
Cobaltochelatase; KEGG- dal-Dalk_4060 cobaltochelatase; PFAM- CobN/magnesium chelatase (1344 aa)
 
   
  0.613
Mvol_1309
Phytoene dehydrogenase and related protein-like protein; KEGG- ftw-FTW_0384 putative flavin containing amine oxidoreductase (414 aa)
   
   
  0.612
Mvol_0369
KEGG- nis-NIS_0367 anaerobic glycerol-3-phosphate dehydrogenase subunit C; TIGRFAM- succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM- protein of unknown function DUF224 cysteine-rich region domain protein; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein (540 aa)
         
  0.586
Mvol_0688
KEGG- sfu-Sfum_0497 magnesium chelatase; SMART- AAA ATPase (356 aa)
 
   
  0.514
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily (356 aa)
           
  0.471
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
Server load: low (9%) [HD]