node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mboo_0225 | Mboo_0227 | Mboo_0225 | Mboo_0227 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | 0.999 |
Mboo_0225 | Mboo_1561 | Mboo_0225 | Mboo_1561 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mhu:Mhun_1032 prephenate dehydratase. | 0.692 |
Mboo_0225 | aroE | Mboo_0225 | Mboo_1563 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.917 |
Mboo_0225 | hisF | Mboo_0225 | Mboo_0659 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.686 |
Mboo_0225 | hisI | Mboo_0225 | Mboo_1916 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.620 |
Mboo_0225 | trpA | Mboo_0225 | Mboo_0222 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate; Belongs to the TrpA family. | 0.999 |
Mboo_0225 | trpB-2 | Mboo_0225 | Mboo_0223 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
Mboo_0225 | trpD | Mboo_0225 | Mboo_0226 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
Mboo_0225 | trpE | Mboo_0225 | Mboo_0228 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. | 0.999 |
Mboo_0225 | trpF | Mboo_0225 | Mboo_0224 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mhu:Mhun_1789 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. | 0.999 |
Mboo_0227 | Mboo_0225 | Mboo_0227 | Mboo_0225 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mhu:Mhun_1788 indole-3-glycerol-phosphate synthase. | 0.999 |
Mboo_0227 | Mboo_1561 | Mboo_0227 | Mboo_1561 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: mhu:Mhun_1032 prephenate dehydratase. | 0.668 |
Mboo_0227 | aroE | Mboo_0227 | Mboo_1563 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.942 |
Mboo_0227 | hisF | Mboo_0227 | Mboo_0659 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.593 |
Mboo_0227 | hisI | Mboo_0227 | Mboo_1916 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.564 |
Mboo_0227 | trpA | Mboo_0227 | Mboo_0222 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate; Belongs to the TrpA family. | 0.995 |
Mboo_0227 | trpB-2 | Mboo_0227 | Mboo_0223 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
Mboo_0227 | trpD | Mboo_0227 | Mboo_0226 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
Mboo_0227 | trpE | Mboo_0227 | Mboo_0228 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. | 0.999 |
Mboo_0227 | trpF | Mboo_0227 | Mboo_0224 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mhu:Mhun_1786 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: mhu:Mhun_1789 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. | 0.999 |