STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fae-hpsOrotidine 5'-phosphate decarboxylase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. (393 aa)    
Predicted Functional Partners:
Mboo_1199
PFAM: sugar isomerase (SIS); KEGG: mhu:Mhun_0910 sugar isomerase (SIS).
 
 0.997
ftr
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
  
 0.973
Mboo_0993
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; PFAM: formylmethanofuran: tetrahydromethanopterin formyltransferase (Ftr); KEGG: mhu:Mhun_1808 formylmethanofuran--tetrahydromethanopterin N-formyltransferase.
 
  
 0.973
Mboo_0707
PFAM: Orotidine 5'-phosphate decarboxylase; Dimethylmenaquinone methyltransferase; KEGG: mhu:Mhun_0647 orotidine 5'-phosphate decarboxylase.
 
  
0.935
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.932
Mboo_1043
PFAM: Tetrahydromethanopterin S-methyltransferase, MtrH subunit; KEGG: afu:AF0009 N5-methyltetrahydromethanopterin:coenzyme M methyltransferase.
  
  
 0.922
mtd
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
     
 0.918
Mboo_0566
TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase, MtrH subunit; KEGG: mhu:Mhun_2175 N5-methyltetrahydromethanopterin.
  
  
 0.918
mtrC
Tetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
     
 0.918
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.918
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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