node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mboo_0473 | Mboo_1118 | Mboo_0473 | Mboo_1118 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.967 |
Mboo_0473 | Mboo_1205 | Mboo_0473 | Mboo_1205 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | KEGG: mhu:Mhun_3032 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region. | 0.997 |
Mboo_0473 | Mboo_1890 | Mboo_0473 | Mboo_1890 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; KEGG: mhu:Mhun_3012 phosphoribosylglycinamide formyltransferase. | 0.999 |
Mboo_0473 | folD | Mboo_0473 | Mboo_2188 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.627 |
Mboo_0473 | purC | Mboo_0473 | Mboo_2202 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | KEGG: mhu:Mhun_1253 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.997 |
Mboo_0473 | purD | Mboo_0473 | Mboo_0840 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | KEGG: mhu:Mhun_1112 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | 0.999 |
Mboo_0473 | purE | Mboo_0473 | Mboo_0052 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
Mboo_0473 | purF | Mboo_0473 | Mboo_0095 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.999 |
Mboo_0473 | purL | Mboo_0473 | Mboo_0472 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.999 |
Mboo_0473 | purM | Mboo_0473 | Mboo_0088 | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | KEGG: mhu:Mhun_3055 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.999 |
Mboo_1118 | Mboo_0473 | Mboo_1118 | Mboo_0473 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mhu:Mhun_1062 phosphoribosylformylglycinamidine synthase I. | 0.967 |
Mboo_1118 | Mboo_1205 | Mboo_1118 | Mboo_1205 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mhu:Mhun_3032 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region. | 0.999 |
Mboo_1118 | Mboo_1890 | Mboo_1118 | Mboo_1890 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; KEGG: mhu:Mhun_3012 phosphoribosylglycinamide formyltransferase. | 0.955 |
Mboo_1118 | folD | Mboo_1118 | Mboo_2188 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.773 |
Mboo_1118 | purC | Mboo_1118 | Mboo_2202 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mhu:Mhun_1253 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.999 |
Mboo_1118 | purD | Mboo_1118 | Mboo_0840 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mhu:Mhun_1112 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase. | 0.994 |
Mboo_1118 | purE | Mboo_1118 | Mboo_0052 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.996 |
Mboo_1118 | purF | Mboo_1118 | Mboo_0095 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.998 |
Mboo_1118 | purL | Mboo_1118 | Mboo_0472 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.991 |
Mboo_1118 | purM | Mboo_1118 | Mboo_0088 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mhu:Mhun_0824 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mhu:Mhun_3055 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.977 |