STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (270 aa)    
Predicted Functional Partners:
Mboo_1351
PFAM: inositol monophosphatase; KEGG: mhu:Mhun_0903 inositol-1(or 4)-monophosphatase.
 
  
 0.986
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
  
 0.967
Mboo_1316
KEGG: aeh:Mlg_2770 pyridine nucleotide transhydrogenase subunit alpha.
     
 0.934
Mboo_1731
KEGG: mhu:Mhun_2915 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; nicotinamide-nucleotide adenylyltransferase; PFAM: cytidylyltransferase.
    
 0.927
Mboo_1315
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: aeh:Mlg_2771 NAD(P)(+) transhydrogenase (AB-specific).
    
 0.916
Mboo_1317
PFAM: NAD(P) transhydrogenase, beta subunit; KEGG: ttj:TTHA0208 nicotinamide nucleotide transhydrogenase, beta subunit.
     
 0.915
Mboo_0886
PFAM: NUDIX hydrolase; KEGG: mac:MA1439 NAD+ pyrophosphatase.
     
 0.912
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
   
 
 0.830
eIF5A
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
       0.682
Mboo_2209
Farnesyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: mhu:Mhun_2886 farnesyltranstransferase; Belongs to the FPP/GGPP synthase family.
 
 
 
 0.623
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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