STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmBProteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (213 aa)    
Predicted Functional Partners:
psmA
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.974
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
 
 0.945
Mboo_1458
KEGG: mhu:Mhun_1040 26S proteasome subunit P45 family; TIGRFAM: 26S proteasome subunit P45 family; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family.
 
 0.943
Mboo_0210
KEGG: mhu:Mhun_2403 hypothetical protein.
   
 0.938
rpl40e
PFAM: Ribosomal protein L40e; KEGG: mhu:Mhun_2870 ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.881
Mboo_1385
PFAM: beta-lactamase domain protein; KH, type 1, domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: mhu:Mhun_0845 beta-lactamase-like.
     
 0.850
Mboo_1596
KEGG: afu:AF1297 cell division control protein 48, AAA family (cdc48-1); TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
 
 0.824
Mboo_2427
KEGG: mhu:Mhun_2451 AAA family ATPase, CDC48 subfamily; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
 
 0.822
Mboo_0486
PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: mhu:Mhun_2338 AAA ATPase, central region; Belongs to the AAA ATPase family.
  
 0.791
Mboo_1386
PFAM: major facilitator superfamily MFS_1; KEGG: mhu:Mhun_0844 major facilitator superfamily MFS_1.
 
     0.735
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.