STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfdAPrefoldin, alpha subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (180 aa)    
Predicted Functional Partners:
pfdB
Prefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
 0.992
rpl21e
PFAM: ribosomal protein L21e; KEGG: mhu:Mhun_3026 ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
    0.874
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.835
srp54
GTP-binding signal recognition particle SRP54, G- domain; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
    0.822
Mboo_0199
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: mhu:Mhun_2549 thermosome.
   
 
 0.775
Mboo_0315
TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1; KEGG: mhu:Mhun_2549 thermosome.
   
 
 0.775
Mboo_0320
PFAM: chaperonin Cpn60/TCP-1; KEGG: mhu:Mhun_0972 chaperonin Cpn60/TCP-1; Belongs to the TCP-1 chaperonin family.
   
 
 0.775
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.775
Mboo_2395
PFAM: chaperonin Cpn60/TCP-1; KEGG: mhu:Mhun_0972 chaperonin Cpn60/TCP-1; Belongs to the TCP-1 chaperonin family.
   
 
 0.775
rpl31e
PFAM: Ribosomal protein L31e; KEGG: mhu:Mhun_3019 ribosomal protein L31e; Belongs to the eukaryotic ribosomal protein eL31 family.
  
  
 0.765
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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