STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
Mboo_1945Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (398 aa)    
Predicted Functional Partners:
Mboo_1843
UbiA prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
 
 0.977
Mboo_1946
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mhu:Mhun_1124 4Fe-4S ferredoxin, iron-sulfur binding.
 
  
 0.940
carS
Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
     
 0.913
Mboo_1947
KEGG: rso:RSp0886 probable glutamine synthetase protein; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp.
     
 0.522
Mboo_2209
Farnesyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: mhu:Mhun_2886 farnesyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.466
Mboo_1981
PFAM: UbiA prenyltransferase; KEGG: mac:MA4010 hypothetical protein.
  
  
 0.454
Mboo_0029
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mhu:Mhun_1746 4Fe-4S ferredoxin, iron-sulfur binding.
 
  
 0.449
nifH-2
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
 
  
 0.426
Mboo_2083
Nitrogenase; PFAM: NifH/frxC-family protein; KEGG: mhu:Mhun_0793 nitrogenase; Belongs to the NifH/BchL/ChlL family.
 
  
 0.402
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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