node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABZ96615.1 | ABZ96619.1 | LEPBI_I0477 | LEPBI_I0481 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.560 |
ABZ96615.1 | hfq | LEPBI_I0477 | LEPBI_I0479 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.821 |
ABZ96615.1 | manC | LEPBI_I0477 | LEPBI_I0480 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Mannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.733 |
ABZ96615.1 | miaA | LEPBI_I0477 | LEPBI_I0478 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.862 |
ABZ96615.1 | pdxJ | LEPBI_I0477 | LEPBI_I0476 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Pyridoxal phosphate biosynthetic protein PdxJ (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.724 |
ABZ96619.1 | ABZ96615.1 | LEPBI_I0481 | LEPBI_I0477 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.560 |
ABZ96619.1 | hfq | LEPBI_I0481 | LEPBI_I0479 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.549 |
ABZ96619.1 | manC | LEPBI_I0481 | LEPBI_I0480 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Mannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.631 |
ABZ96619.1 | miaA | LEPBI_I0481 | LEPBI_I0478 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.563 |
ABZ96619.1 | pdxJ | LEPBI_I0481 | LEPBI_I0476 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Pyridoxal phosphate biosynthetic protein PdxJ (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.497 |
dxs | pdxJ | LEPBI_I2605 | LEPBI_I0476 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Pyridoxal phosphate biosynthetic protein PdxJ (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.598 |
dxs | ribBA | LEPBI_I2605 | LEPBI_I1406 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.577 |
gcvP | pdxH | LEPBI_I3190 | LEPBI_I1407 | Glycine dehydrogenase [decarboxylating] (Glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.447 |
gcvP | pdxJ | LEPBI_I3190 | LEPBI_I0476 | Glycine dehydrogenase [decarboxylating] (Glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyridoxal phosphate biosynthetic protein PdxJ (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.539 |
hfq | ABZ96615.1 | LEPBI_I0479 | LEPBI_I0477 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.821 |
hfq | ABZ96619.1 | LEPBI_I0479 | LEPBI_I0481 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.549 |
hfq | manC | LEPBI_I0479 | LEPBI_I0480 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Mannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.763 |
hfq | miaA | LEPBI_I0479 | LEPBI_I0478 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.942 |
hfq | pdxJ | LEPBI_I0479 | LEPBI_I0476 | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Pyridoxal phosphate biosynthetic protein PdxJ (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.698 |
manC | ABZ96615.1 | LEPBI_I0480 | LEPBI_I0477 | Mannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.733 |