STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase (biotin synthetase); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (351 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.998
bioA
7,8-diamino-pelargonic acid aminotransferase; DAPA aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.993
bioF
8-amino-7-oxononanoate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.936
birA
BirA bifunctional protein; Function of homologous gene experimentally demonstrated in an other organism; putative factor.
  
 
 0.919
ABZ96956.1
Putative sodium/galactoside symporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
       0.747
ABZ96957.1
Hypothetical protein; Doubtful CDS.
       0.730
ABZ96958.1
Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.707
serB
PSP; O-phosphoserine phosphohydrolase; PSPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.706
ABZ96951.1
Putative permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
       0.534
ABZ96952.1
Putative cAMP-dependent protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.520
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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