STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbpFructose-1,6-bisphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (383 aa)    
Predicted Functional Partners:
tal
Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.939
pgi
GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.
   
 
 0.932
pfkA
Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
    
 0.932
fbaB
Fructose-bisphosphate aldolase class I (FBP aldolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.922
manA
Mannose-6-phosphate isomerase (Phosphomannose isomerase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.908
ABZ96777.1
Putative transketolase (TK); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
ABZ99035.1
Putative transketolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
ABZ97670.1
Hypothetical protein; No homology to any previously reported sequences.
       0.741
icd
Isocitrate dehydrogenase (NADP); Oxalosuccinate decarboxylase; IDH; NADP(+)-specific ICDH; IDP; CtIDP1); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
  
 0.698
ABZ97668.1
Hypothetical protein; No homology to any previously reported sequences.
       0.680
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.