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RSAG_00165 protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"RSAG_00165" - 5-formyltetrahydrofolate cyclo-ligase in Ruminococcus sp. 5139BFAA
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSAG_001655-formyltetrahydrofolate cyclo-ligase (185 aa)    
Predicted Functional Partners:
RSAG_00609
Uncharacterized protein (209 aa)
       
    0.977
RSAG_00166
UPF0291 protein RSAG_00166 (73 aa)
            0.970
proA
Glutamyl-gamma-semialdehyde dehydrogenase ; Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate (422 aa)
              0.879
folD
Bifunctional protein FolD ; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (284 aa)
   
  0.876
purN
GAR transformylase ; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (213 aa)
   
 
  0.837
glyA
Serine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (412 aa)
   
  0.760
proB
Gamma-glutamyl kinase ; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate (285 aa)
              0.728
ybeY
Endoribonuclease YbeY ; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3’ terminus of the 16S rRNA (164 aa)
     
      0.724
RSAG_00170
Uncharacterized protein (336 aa)
 
          0.700
fhs
Formyltetrahydrofolate synthetase (561 aa)
   
  0.682
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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